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Amifostine trihydrate is a broad-spectrum cytoprotection agent against the DNA damaging effects of ionizing radiation. Amifostine trihydrate selectively protects normal tissues from the damaging effects of anti-neoplastic radiation therapy. Selectivity is due to preferential uptake by normal tissues and subsequent metabolic activation to 2-(3-aminopropyl)aminoethanethiol.
| Molecular Weight | 268.27 |
| Formula | C5H15N2O3PS.3H2O |
| CAS Number | 112901-68-5 |
| Solubility (25°C) | Water ≥ 30 mg/mL |
| Storage | 2-8°C, dry, protect from light, sealed |
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