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ALZ-801

Cat. No. M21812

All AbMole products are for research use only, cannot be used for human consumption.

ALZ-801 Structure
Synonym:

Valiltramiprosate; NRM-8499; BLU8499

Size Price Availability Quantity
5mg USD 110  USD110 In stock
10mg USD 190  USD190 In stock
25mg USD 420  USD420 In stock
50mg USD 750  USD750 In stock
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Quality Control & Documentation
Biological Activity

ALZ-801 is an orally active small molecule compound that is also an inhibitor of β-amyloid A4 (APP) and a precursor compound of homotaurine, which inhibits the formation of neurotoxic amyloid oligomers, and may be used in studies related to Alzheimer's disease (AD).

Chemical Information
Molecular Weight 238.3
Formula C8H18N2O4S
CAS Number 1034190-08-3
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Martin Tolar, et al. Int J Mol Sci. Neurotoxic Soluble Amyloid Oligomers Drive Alzheimer's Pathogenesis and Represent a Clinically Validated Target for Slowing Disease Progression

[2] Martin Tolar, et al. Alzheimers Res Ther. Aducanumab, gantenerumab, BAN2401, and ALZ-801-the first wave of amyloid-targeting drugs for Alzheimer's disease with potential for near term approval

[3] Martin Tolar, et al. Alzheimers Dement. The path forward in Alzheimer's disease therapeutics: Reevaluating the amyloid cascade hypothesis

[4] John A Hey, et al. Clin Pharmacokinet. Clinical Pharmacokinetics and Safety of ALZ-801, a Novel Prodrug of Tramiprosate in Development for the Treatment of Alzheimer's Disease

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Keywords: ALZ-801, Valiltramiprosate; NRM-8499; BLU8499 supplier, Amyloid, inhibitors, activators

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