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α-Cyperone

Cat. No. M4729

All AbMole products are for research use only, cannot be used for human consumption.

α-Cyperone Structure
Synonym:

α-Cyperone; (+)-α-Cyperone

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20mg USD 180  USD180 In stock
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Biological Activity

Alpha-cyperone (α -cyperone) is associated with down-regulated expression of COX-2, IL-6, NCK-2, Cdc42, and Rac1, thereby reducing the inflammatory response.

*The compound is unstable in solutions, freshly prepared is recommended


Chemical Information
Molecular Weight 218.33
Formula C15H22O
CAS Number 473-08-5
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Huawei Zhang, et al. α-Cyperone (CYP) down-regulates NF-κB and MAPKs signaling, attenuating inflammation and extracellular matrix degradation in chondrocytes, to ameliorate osteoarthritis in mice

[2] Connor Horn, et al. Anticapsular and Antifungal Activity of α-Cyperone

[3] Bingxu Huang, et al. α-Cyperone Attenuates H 2 O 2-Induced Oxidative Stress and Apoptosis in SH-SY5Y Cells via Activation of Nrf2

[4] Bingxu Huang, et al. α-Cyperone inhibits LPS-induced inflammation in BV-2 cells through activation of Akt/Nrf2/HO-1 and suppression of the NF-κB pathway

[5] Yu Ma, et al. α-Cyperone Inhibits PMA-Induced EPCR Shedding through PKC Pathway

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Keywords: α-Cyperone, α-Cyperone; (+)-α-Cyperone supplier, Metabolite/Endogenous Metabolite, inhibitors, activators

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