All AbMole products are for research use only, cannot be used for human consumption.
Allicin has highly potent antimicrobial activity, and inhibits growth of a variety of microorganisms, among them antibiotic-resistant strains.
For the in vitro study, a stock solution of 15 mM for allicin was prepared in DMSO and stored at –20°C. For each experiment, the stock solution of allicin was diluted with DMEM to obtain a series of concentrations (15, 30 and 60 µM). The final DMSO concentration was 0.1% (v/v).
For the in vivo study, allicin was dissolved in normal saline to final concentrations of 0.5, 1, and 2 mg/ml. The dosing volume of allicin was determined based on the body weight of each animal, for example, 0.2 ml for a 20 g mouse.
https://pubmed.ncbi.nlm.nih.gov/25730897/
Allicin can be stored in methanol at -20°C. Allicin is very stable under these conditions; degradation is less than 1% for more than 2 years. Methanol was removed and allicin was dissolved in 0.5% carboxymethylcellulose (CMC) before administering to the mice. Preparations were made every 2 weeks. The half degradation time (DT50) of allicin in 0.5% CMC was 11.35 days at -20°C, according to https://pubmed.ncbi.nlm.nih.gov/27584700/.
| Molecular Weight | 162.27 |
| Formula | C6H10OS2 |
| CAS Number | 539-86-6 |
| Form | Liquid |
| Solubility (25°C) | DMSO ≥ 60 mg/mL |
| Storage | 2-8°C, dry, sealed, protect from light |
[4] Jan Borlinghaus, et al. Allicin: chemistry and biological properties
[5] S Ankri, et al. Antimicrobial properties of allicin from garlic
| Related Antibiotic Products |
|---|
| Puromycin-d3
Puromycin-d3 is the deuterium labeled Puromycin. Puromycin dihydrochloride is the dihydrochloride salt of puromycin. Puromycin is an aminoglycoside antibiotic that inhibits protein synthesis. |
| BSH-IN-1
BSH-IN-1 is a potent and covalent inhibitor of gut bacterial recombinant bile salt hydrolases (BSHs) with IC50s of 108 nM and 427 nM for B. longum BSH (Gram positive) and B. theta BSH (Gram negative), respectively. |
| AAA-10
AAA-10 is an orally active gut bacterial bile salt hydrolases (BSH) inhibitor, with IC50s of 10 nM, 80 nM against B. theta rBSH and B. longum rBSH respectively. |
| Gut restricted-7
Gut restricted-7 (GR-7) is a potent, covalent and orally active pan-bile salt hydrolase (BSH) inhibitor. Gut restricted-7 has a tissue-selective and is restricted to the gut. Gut restricted-7 decreases gut bacterial BSHs and decreases deconjugated bile acid levels in feces of mice. |
| N-Hydroxypipecolic acid
N-Hydroxypipecolic acid (1-Hydroxy-2-piperidinecarboxylic acid), a plant metabolite and a systemic acquired resistance (SAR) regulator, orchestrates SAR establishment in concert with the immune signal salicylic acid. N-Hydroxypipecolic acid accumulates systemically in the plant foliage in response to pathogen attack. N-Hydroxypipecolic acid induces SAR to bacterial and oomycete infection. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
