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Alemtuzumab

Cat. No. M3847

All AbMole products are for research use only, cannot be used for human consumption.

Alemtuzumab Structure
Synonym:

Campath-1H

Size Price Availability Quantity
2mg USD 900  USD900 In stock
5mg USD 1200  USD1200 In stock
10mg USD 1800  USD1800 In stock
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Quality Control & Documentation
Biological Activity

Alemtuzumab is a monoclonal antibody that binds to CD52, a protein present on the surface of mature lymphocytes, but not on the stem cells from which these lymphocytes are derived. After treatment with alemtuzumab, these CD52-bearing lymphocytes are targeted for destruction. Alemtuzumab does not cross-react with mouse CD52, making in vivo studies in wild-type mice unfeasible.

Chemical Information
Molecular Weight 145451.73
Formula C6468H10066N1732O2005S40
CAS Number 216503-57-0
Storage -80°C for long term
References

[1] Ruxrungtham K, et al. J Virus Erad. Alemtuzumab-induced elimination of HIV-1-infected immune cells.

[2] Mark S Freedman, et al. J Clin Cell Immunol. Insights into the Mechanisms of the Therapeutic Efficacy of Alemtuzumab in Multiple Sclerosis

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Keywords: Alemtuzumab, Campath-1H supplier, inhibitors, activators

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