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Alemtuzumab is a monoclonal antibody that binds to CD52, a protein present on the surface of mature lymphocytes, but not on the stem cells from which these lymphocytes are derived. After treatment with alemtuzumab, these CD52-bearing lymphocytes are targeted for destruction. Alemtuzumab does not cross-react with mouse CD52, making in vivo studies in wild-type mice unfeasible.
Molecular Weight | 145451.73 |
Formula | C6468H10066N1732O2005S40 |
CAS Number | 216503-57-0 |
Storage | -80°C for long term |
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