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ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine.
| Molecular Weight | 766.27 |
| Formula | C48H95NO5 |
| CAS Number | 2036272-55-4 |
| Solubility (25°C) | DMSO 50 mg/mL Ethanol 80 mg/mL |
| Storage | 4°C, protect from light |
[2] S Moein Moghimi. Mol Ther. Allergic Reactions and Anaphylaxis to LNP-Based COVID-19 Vaccines
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