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AGI-43192 is a potent inhibitor of methionine adenosyltransferase 2A (MAT2A). AGI-43192 is a potent, but limited brain-penetrant compound. AGI-43192 has the potential for exploring the effects of SAM modulation in the central nervous system (CNS) and research of cancer disease.
| Molecular Weight | 484.86 |
| Formula | C23H16ClF3N6O |
| CAS Number | 2377491-54-6 |
| Form | Solid |
| Solubility (25°C) | DMSO 13.89 mg/mL (ultrasonic and warming and heat to 60°C) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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