Free shipping on all orders over $ 500

AF64394

Cat. No. M9494

All AbMole products are for research use only, cannot be used for human consumption.

AF64394 Structure
Synonym:

AF-64394

Size Price Availability Quantity
5mg USD 155  USD155 In stock
10mg USD 250  USD250 In stock
25mg USD 525  USD525 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

AF64394 is a selective GPR3 inverse agonist with a pIC50 of 7.3.

Chemical Information
Molecular Weight 393.87
Formula C21H20ClN5O
CAS Number 1637300-25-4
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Jensen T, et al. Bioorg Med Chem Lett. The identification of GPR3 inverse agonist AF64394; the first small molecule inhibitor of GPR3 receptor function.

Related GPR/FFAR Products
CID1231538

CID1231538 is a potent GPR35 antagonist, with IC50 of 0.55 μM. CID1231538 is a benzothiazole analogue.

[Ala17]-MCH

[Ala17]-MCH, a MCH analogue, is a selective ligand for MCHR1 (Ki=0.16 nM) over MCHR2 (Ki=34 nM).

BigLEN(rat)

BigLEN(rat) is a potent GPR171 agonist with an EC50 of 1.6 nM.

BigLEN(mouse)

BigLEN(mouse) is a potent and selective agonist of orphan G protein-coupled receptor 171 (GPR171), with a Kd of ∼0.5 nM.

Neuropeptide EI, rat

Neuropeptide EI, rat displays functional melanin concentrating hormone (MCH)-antagonist and melanocyte-stimulating hormone (MSH) agonist activity in different behavioral paradigms.

  Catalog
Abmole Inhibitor Catalog




Keywords: AF64394, AF-64394 supplier, GPR/FFAR, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.