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AF12198 is a potent, selective and specific peptide antagonist for human type I interleukin-1 receptor (IL1-R1) (IC50=8 nM) but not the human type II receptor (IC50=6.7 µM) or the murine type I receptor (IC50>200 µM).
| Molecular Weight | 1895.12 |
| Formula | C96H123N19O22 |
| CAS Number | 185413-30-3 |
| Form | Solid |
| Solubility (25°C) | DMSO 90 mg/mL |
| Storage | -20°C, protect from light, dry, sealed |
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