Product Name: | AF12198 |
Catalog Number: | M54008 |
CAS Number: | 185413-30-3 |
Formula: | C96H123N19O22 |
Molecular Weight: | 1895.12 |
Form: | Solid |
Solubility: | DMSO 90 mg/mL |
Storage: | -20°C, protect from light, dry, sealed |
Chemical Structure: | ![]() |
QC Standard: | >99.5% |
H-NMR: | Consistent with structure |
Description: | AF12198 is a potent, selective and specific peptide antagonist for human type I interleukin-1 receptor (IL1-R1) (IC50=8 nM) but not the human type II receptor (IC50=6.7 µM) or the murine type I receptor (IC50>200 µM). |
Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |