Certificate of Analysis

 

Product Name: AF12198
Catalog Number: M54008
CAS Number: 185413-30-3

Physical and Chemical Properties
Formula: C96H123N19O22
Molecular Weight: 1895.12
Form: Solid
Solubility: DMSO 90 mg/mL
Storage: -20°C, protect from light, dry, sealed
Chemical Structure: AF12198 Structure
Analytical Data
QC Standard: >99.5%
H-NMR: Consistent with structure
Product Information
Description: AF12198 is a potent, selective and specific peptide antagonist for human type I interleukin-1 receptor (IL1-R1) (IC50=8 nM) but not the human type II receptor (IC50=6.7 µM) or the murine type I receptor (IC50>200 µM).
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.