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Acetylethylcholine mustard hydrochloride

Cat. No. M7679

All AbMole products are for research use only, cannot be used for human consumption.

Acetylethylcholine mustard hydrochloride Structure

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Quality Control & Documentation
Biological Activity

Acetylethylcholine mustard is a precursor for ethylcholine mustard aziridinium ion (AF-64A); irreversible ligand for the high affinity choline transport system; specific presynaptic long action cholinotoxin; inhibitor of choline acetyl-transferase.

Chemical Information
Molecular Weight 230.13
Formula C8H16ClNO2 · HCl
CAS Number 103994-00-9
Solubility (25°C) Water: ≥5 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] L W Zhou, et al. AF64A lesions of mouse striatum result in ipsilateral rotations to D2 dopamine agonists but contralateral rotations to muscarinic cholinergic agonists

[2] B J Morley, et al. AF64 depletes hypothalamic high-affinity choline uptake and disrupts the circadian rhythm of locomotor activity without altering the density of nicotinic acetylcholine receptors

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