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Acamprosate, or N-acetyl homotaurine, is an N-methyl-D-aspartate receptor modulator approved by the Food and Drug Administration (FDA) as a pharmacological treatment for alcohol dependence.Acamprosate has low bioavailability, but also has an excellent tolerability and safety profile. In comparison with naltrexone and disulfiram, which are the other FDA-approved treatments for alcohol dependence, acamprosate is unique in that it is not metabolized by the liver and is also not impacted by alcohol use, so can be administered to patients with hepatitis or liver disease (a common comorbid condition among individuals with alcohol dependence) and to patients who continue drinking alcohol.
Molecular Weight | 200.24 |
Formula | 2(C5H10NO4S).Ca |
CAS Number | 77337-73-6 |
Form | Solid |
Solubility (25°C) | H2O 90 mg/mL |
Storage | 4°C, dry, sealed |
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