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A-1165442

Cat. No. M14276

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A-1165442 Structure
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Biological Activity

A-1165442 is a potent, competitive and orally available TRPV1 antagonist with an IC50 of 9 nM for human TRPV1.

Chemical Information
Molecular Weight 431.86
CAS Number 1221443-94-2
Solubility (25°C)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Eric A Voight, et al. J Med Chem. Discovery of (R)-1-(7-chloro-2,2-bis(fluoromethyl)chroman-4-yl)-3-(3-methylisoquinolin-5-yl)urea (A-1165442): a temperature-neutral transient receptor potential vanilloid-1 (TRPV1) antagonist with analgesic efficacy

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Keywords: A-1165442 supplier, TRP Channel, inhibitors, activators

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