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erythro-Guaiacylglycerol-β-O-4'-dehydrodisinapyl ether

Cat. No. M40151
erythro-Guaiacylglycerol-β-O-4'-dehydrodisinapyl ether Structure
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Biological Activity

erythro-Guaiacylglycerol-β-O-4'-dehydrodisinapyl ether (Compound 122) inhibits lettuce germination. erythro-Guaiacylglycerol-β-O-4'-dehydrodisinapyl ether can be isolated from Brassica fruticulosa.

Chemical Information
Molecular Weight 584.61
Formula C31H36O11
CAS Number 613684-55-2
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Miao Cao et al. Sci Total Environ. 2,2',4,4'-tetrabromodiphenyl ether causes depigmentation in zebrafish larvae via a light-mediated pathway

[2] Isabel Cristina Legarda. J Med Humanit. Ether Dome

[3] J Leach et al. Phys Rev Lett. Leach et al. Reply

[4] C P BOYAN. Med Times. Ether anesthesia

[5] R A Peters. Biochem Pharmacol. Ether-O-oxidase

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