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6"-O-Acetyldaidzin 

Cat. No. M30526
6
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Biological Activity

6"-O-Acetyldaidzin is an isoflavone glycoside isolated from soybeans. 6"-O-Acetyldaidzin significantly inhibits lipid peroxidation in rat liver microsome with an IC50 of 8.2 μM.

Chemical Information
Molecular Weight 458.41
Formula C23H22O10
CAS Number 71385-83-6
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Heloisa Gabriel Falcão, et al. Food Chem. Soybean ultrasound pre-treatment prior to soaking affects β-glucosidase activity, isoflavone profile and soaking time

[2] Shuai Wu, et al. Zhongguo Zhong Yao Za Zhi. [Studies on biotransformation of chemical constituents of tongmai formula by human intestinal flora]

[3] L J Chen, et al. J Chromatogr A. Quantitative determination and structural characterization of isoflavones in nutrition supplements by liquid chromatography-mass spectrometry

[4] Helen Wiseman, et al. J Agric Food Chem. Isoflavone aglycon and glucoconjugate content of high- and low-soy U.K. foods used in nutritional studies

[5] S J Lee, et al. Planta Med. An antioxidant lignan and other constituents from the root bark of Hibiscus syriacus

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