6-Dimethylaminopurine is a serine threonine protein kinase inhibitor. It inhibits the germinal vesicle breakdown and the meiotic maturation of oocytes.
|Solubility (25°C)||DMSO 32 mg/mL|
Powder -20°C 3 years ; 4°C 2 years
In solvent -80°C 6 months ; -20°C 1 month
|Body Surface Area (m2)||0.007||0.025||0.15||0.05||0.02||0.5|
|Animal A (mg/kg) = Animal B (mg/kg) multiplied by||Animal B Km|
|Animal A Km|
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
 Irina V Ogneva, et al. Int J Mol Sci. Sperm of Fruit Fly Drosophila melanogaster under Space Flight
 Irina V Ogneva. Curr Issues Mol Biol. Mouse and Fly Sperm Motility Changes Differently under Modelling Microgravity
 Jilong Zhou, et al. Aging (Albany NY). Resveratrol delays postovulatory aging of mouse oocytes through activating mitophagy
 Karolina Kubiasov, et al. Phytochemistry. Design, synthesis and perception of fluorescently labeled isoprenoid cytokinins
 J Nath, et al. Exp Cell Res. Studies on cyclic AMP levels and phosphodiesterase activity in developing sea urchin eggs. Effects of puromycin, 6-dimethylamino purine and aminophylline
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