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5S rRNA modificator

Cat. No. M28367

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5S rRNA modificator Structure
Synonym:

FAI

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Biological Activity

5S rRNA modificator is a suitable electrophile for 2’-hydroxyl acylation on structured RNA molecules, yielding accurate structural information comparable to that obtained with existing probes; 5S rRNA RNA modification.

Chemical Information
Molecular Weight 176.17
Formula C9H8N2O2
CAS Number 1415238-77-5
Form Solid
Solubility (25°C) DMSO ≥ 52 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Mikael S Lindström, et al. Cell Death Differ. p53 at the crossroad of DNA replication and ribosome biogenesis stress pathways

[2] J Douet, et al. Heredity (Edinb). Transcription of the 5S rRNA heterochromatic genes is epigenetically controlled in Arabidopsis thaliana and Xenopus laevis

[3] Benjamin Lau, et al. EMBO Rep. Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis

[4] O A Dontsova, et al. Nauchnye Doki Vyss Shkoly Biol Nauki. [The 5S rRNA-protein complex of Escherichia coli studied by carbodiimide modification]

[5] E Bruenger, et al. FASEB J. 5S rRNA modification in the hyperthermophilic archaea Sulfolobus solfataricus and Pyrodictium occultum

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Keywords: 5S rRNA modificator, FAI supplier, inhibitors, activators

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