Free shipping on all orders over $ 500

4-Methyl-2-oxopentanoic acid

Cat. No. M14349

All AbMole products are for research use only, cannot be used for human consumption.

4-Methyl-2-oxopentanoic acid Structure
Synonym:

α-Ketoisocaproic acid

Size Price Availability Quantity
250mg USD 60  USD60 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

4-Methyl-2-oxopentanoic acid (α-Ketoisocaproic acid) is a metabolite of L-leucine and is involved in energy metabolism. 4-Methyl-2-oxopentanoic acid increases endoplasmic reticulum stress, promotes lipid accumulation in preadipocytes and insulin resistance by impairing mTOR and autophagy signaling pathways. 4-Methyl-2-oxopentanoic acid acts as a nutrient signal and stimulates skeletal muscle protein synthesis.

Chemical Information
Molecular Weight 130.14
Formula C6H10O3
CAS Number 816-66-0
Form Liquid (density 1.055 g/mL)
Solubility (25°C) DMSO 90 mg/mL
Water 90 mg/mL
Storage 2-8°C, protect from light
References

[1] Project Nshimiyimana, et al. Engineering of L-amino acid deaminases for the production of α-keto acids from L-amino acids

[2] J C Brown, et al. Actions of GIP

[3] D B Buxton, et al. Regulatory effects of fatty acids on decarboxylation of leucine and 4-methyl-2-oxopentanoate in the perfused rat heart

[4] J F Tomera, et al. Assessment of the flux of mitochondrial acetyl-CoA in liver and kidney by using the differential production of 14CO2 from tracers of (1-14C)- and (2-14C)-labelled 4-methyl-2-oxovalerate

[5] A E Harper, et al. Branched-chain amino acid metabolism

Related Metabolite/Endogenous Metabolite Products
p-Cresol glucuronide

p-Cresol glucuronide is a metabolite of p-cresol, it is a prototype protein-bound uremic toxin.

Oleamide

Oleamide is an endogenous fatty acid amide.

Deoxycarnitine chloride

Deoxycarnitine chloride is angiopathic substance produced as an intermediary metabolite by gut microbiota.

Monobutyl phthalate

Monobutyl phthalate, a major metabolite of dibutyl phthalate (DBP), possesses antiandrogenic effects. Monobutyl phthalate is an embryotoxicant.

Testosterone sulfate (pyridinium)

Testosterone sulfate pyridinium is a Testosterone sulfate with a pyridinium. Testosterone sulfate is the metabolite of Testosterone.

  Catalog
Abmole Inhibitor Catalog




Keywords: 4-Methyl-2-oxopentanoic acid, α-Ketoisocaproic acid supplier, Metabolite/Endogenous Metabolite, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.