Certificate of Analysis
| Product Name: | 4-Methyl-2-oxopentanoic acid |
| Catalog Number: | M14349 |
| CAS Number: | 816-66-0 |
Physical and Chemical Properties
| Formula: | C6H10O3 |
| Molecular Weight: | 130.14 |
| Form: | Liquid (density 1.055 g/mL) |
| Solubility: | DMSO 90 mg/mL; Water 90 mg/mL |
| Storage: | 2-8°C, protect from light |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | 4-Methyl-2-oxopentanoic acid (α-Ketoisocaproic acid) is a metabolite of L-leucine and is involved in energy metabolism. 4-Methyl-2-oxopentanoic acid increases endoplasmic reticulum stress, promotes lipid accumulation in preadipocytes and insulin resistance by impairing mTOR and autophagy signaling pathways. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |