Free shipping on all orders over $ 500

3,4,5-Trimethoxycinnamic acid

Cat. No. M39022

All AbMole products are for research use only, cannot be used for human consumption.

3,4,5-Trimethoxycinnamic acid Structure

Price and Availability

For this product's availability, delivery time and price, please email [email protected] directly or click the "Inquiry Now" button below.

Quality Control & Documentation
Biological Activity

3,4,5-Trimethoxycinnamic acid has anti-stress effect, prolonging the sleeping time in animals. 3,4,5-Trimethoxycinnamic acid increases expression of GAD65 and γ-subunit of GABAA receptor, but shows no effect on the amounts of α-, β-subunits.

Chemical Information
Molecular Weight 238.24
Formula C12H14O5
CAS Number 90-50-6
Form Solid
Solubility (25°C) DMSO 90 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Eunchong Hong et al. Mol Neurobiol. Derivatives of 3, 4, 5-Trimethoxycinnamic Acid Ameliorate Stress-Induced Anxiety in Mice and Rats

[2] Zefeng Zhao et al. Eur J Med Chem. Research progress in the biological activities of 3,4,5-trimethoxycinnamic acid (TMCA) derivatives

[3] Jae-Chul Jung et al. Chem Biol Drug Des. Synthesis and evaluation of a series of 3,4,5-trimethoxycinnamic acid derivatives as potential antinarcotic agents

[4] M I Donnelly et al. J Bacteriol. Bacterial degradation of 3,4,5-trimethoxycinnamic acid with production of methanol

[5] T Meyer et al. Xenobiotica. 3,4,5-trimethoxycinnamic acid and related compounds. II. Metabolism in the rat

Related GABA Receptor Products
β-CCB 

β-CCB is a ligand for benzodiazepine receptor, which inhibits the binding of [3H]flunitrazepam and ethyl (3-[3H]carboline-3-carboxylate to benzodiazepine receptors, with Ki of 3-4 nM.
TPMPA 

TPMPA, a hybrid of isoguvacine and 3-APMPA, is the first selective antagonist for a GABAC receptor (KB = 2.1 μM), but not to interact with GABAA (KB = 320 μM) or GABAB receptors (EC50 = 500 μM).
CI-966 

CI-966 is a potent, selective, orally active and brain-penetrant inhibitor of the GABA transporter GAT-1, with IC50s of 0.26 μM and 1.2 μM for hGAT-1, rGAT-1, respectively.
NCS-382 

NCS-382 is a potent GABA receptor antagonist and also a GHBR receptor antagonist.
CGS 8216 

CGS 8216, a benzodiazepine receptor antagonist, inhibits 3H-flunitrazepam (3H-FLU) binding to rat synaptosomal membranes in vitro at subnanomolar concentrations.
  Catalog
Abmole Inhibitor Catalog




Keywords: 3,4,5-Trimethoxycinnamic acid supplier, GABA Receptor, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.


 
Get to Know Us
Customer Support
Resources
Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.