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2'3'-cGAMP (2'-3'-cyclic GMP-AMP sodium) is a endogenous cGAMP in mammalian cells. 2'3'-cGAMP binds to STING with a high affinity and is a potent inducer of interferon-β (IFNβ). 2'3'-cGAMP is produced in mammalian cells in response to DNA in the cytoplasm.
| Molecular Weight | 674.41 |
| Formula | C20H24N10O13P2 |
| CAS Number | 1441190-66-4 |
| Solubility (25°C) | Water 4 mg/mL (May need ultrasonic and warming) |
| Storage | -20°C, dry, sealed |
[1] Chen Chen, et al. Trends Cell Biol. Cellular functions of cGAS-STING signaling
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