Certificate of Analysis

 

Product Name: 2'3'-cGAMP
Catalog Number: M21614
CAS Number: 1441190-66-4

Physical and Chemical Properties
Formula: C20H24N10O13P2
Molecular Weight: 674.41
Solubility: Water 4 mg/mL (May need ultrasonic and warming)
Storage: -20°C, dry, sealed
Chemical Structure: 2'3'-cGAMP Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: 2'3'-cGAMP (2'-3'-cyclic GMP-AMP) is a endogenous cGAMP in mammalian cells. 2'3'-cGAMP binds to STING with a high affinity and is a potent inducer of interferon-β (IFNβ). 2'3'-cGAMP is produced in mammalian cells in response to DNA in the cytoplasm.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.