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2,2′-Dipyridyl disulfide

Cat. No. M29274

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2,2′-Dipyridyl disulfide Structure
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Biological Activity

2,2′-Dipyridyl disulfide is a useful reagent for the determination of sulfhydryl groups. 2,2′-Dipyridyl disulfide is a common reagent in peptide chemistry, often used in oxidation–reduction condensations to form peptide bonds or in coupling reactions to form disulfide-linked heterodimers.

Chemical Information
Molecular Weight 220.31
Formula C10H8N2S2
CAS Number 2127-03-9
Form Solid
Solubility (25°C) DMSO 100 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Hua Tian, et al. Aquat Toxicol. mRNA-miRNA sequencing reveals mechanisms of 2,2'-dipyridyl disulfide-induced thyroid disruption in Japanese flounder (Paralichthys olivaceus)

[2] Qianqian Fan, et al. J Phys Chem Lett. Insight into Chemical Reduction and Charge Storage Mechanism of 2,2'-Dipyridyl Disulfide toward Stable Lithium-Organic Battery

[3] Hidekazu Katayama, et al. J Pept Sci. Application of 2,2'-dipyridyl disulfide-mediated thiazolidine ring-opening reaction to glycoprotein synthesis: Total chemical synthesis of evasin-3

[4] K Maruyama, et al. Peptides. 2,2'-Bispyridyl disulfide rapidly induces intramolecular disulfide bonds in peptides

[5] J P Malthouse, et al. Biochem J. A kinetic method for the study of solvent environments of thiol groups in proteins involving the use of a pair of isomeric reactivity probes and a differential solvent effect. Investigation of the active centre of ficin by using 2,2'- and 4,4'- dipyridyl 䲧瘀Ỵ瘁㧀痿羹皘的ࡍţ

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Keywords: 2,2′-Dipyridyl disulfide supplier, inhibitors, activators

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