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15-Deoxy-Δ-12,14-prostaglandin J2 (15d-PGJ2) is a cyclopentenone prostaglandin and a metabolite of PGD2. 15-Deoxy-Δ-12,14-prostaglandin J2 is a selective PPARγ (EC50 of 2 µM) and a covalent PPARδ agonist. 15-Deoxy-Δ-12,14-prostaglandin J2 promotes efficient differentiation of C3H10T1/2 fibroblasts to adipocytes with an EC50 of 7 μM.
| Molecular Weight | 316.43 |
| Formula | C20H28O3 |
| CAS Number | 87893-55-8 |
| Form | Liquid |
| Solubility (25°C) | Ethanol 65 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[4] Qingli Bie, et al. Am J Transl Res. 15d-PGJ2 is a new hope for controlling tumor growth
[5] Jose U Scher, et al. Clin Immunol. 15d-PGJ2: the anti-inflammatory prostaglandin?
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