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URAT1 Uric Acid Transporter 1

Inhibitors

Cat.No.  Name Information
M10691 Dotinurad Dotinurad is a potent selective urate reabsorption inhibitor. Dotinurad inhibits Urate Transporter 1 (URAT1),IC50 The value is 37.2 nM. Dotinurad is used as a uric acid-enhancing excretor.
M5734 Lesinurad Lesinurad is a URAT1 and OAT inhibitor, is determined to be a substrate for the kidney transporters OAT1 and OAT3 with Km values of 0.85 and 2 µM, respectively.



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