Src-bcr-Abl Src-bcr-Abl

Cat.No.	Name	Information
M2331	PP2	PP2 (AGL 1879) is a selective inhibitor of Src-family tyrosine kinases with >10,000-fold selectivity over ZAP-70 and JAK2.
M1701	Dasatinib	Dasatinib (BMS-354825) is a small molecule inhibitor of both the SRC and BCR/ABL tyrosine kinases, with IC50's for the isolated kinases of 0.55 and 3.0 nM, respectively.
M1648	AP24534	Ponatinib (AP24534) is a novel potent, orally available small molecule multitargeted kinase inhibitor of BCR-ABL, PDGFRα, c-Src, c-Kit, FGFR and VEGFR.
M1799	Imatinib Mesylate	Imatinib Mesylate is a Bcr-Abl tyrosine kinase inhibitor, with IC50 values of 2.9 and 3.9 μM for the inhibition of T-cell proliferation stimulated by PHA and DCs respectively.
M1685	Bosutinib	Bosutinib (SKI-606) is a novel Bcr-Abl inhibitor with IC50 values of 0.1 to 0.3 umol/L.
M3194	Nocodazole	Nocodazole is a rapidly-reversible inhibitor of microtubule polymerization, also inhibits Abl, Abl(E255K) and Abl(T315I) with IC50 of 0.21 μM, 0.53 μM and 0.64 μM, respectively.
M1912	Nilotinib	Nilotinib (AMN107) is a small molecule Bcr-Abl kinase inhibitor with IC50 less than 30 nM.
M8118	PD166326	PD166326 is an ATP-competitive inhibitor of BCR-ABL and Src kinases, inhibiting Src and Abl with IC50 values of 6 nM and 8 nM, respectively.