Cat.No. | Name | Information |
---|---|---|
M6635 | CRT0066101 dihydrochloride | CRT 0066101 is a potent protein kinase D (PKD) inhibitor. |
M3747 | CID755673 | CID755673 is a potent and selective cell-active small molecule inhibitor for PKD with an IC50 of 182 nM. |
M2556 | CID-2011756 | CID-2011756 is a cell-active ATP competitive and specific PKD1 inhibitor that inhibits phorbol ester-induced endogenous PKD1 activation in LNCaP prostate cancer cells. |
M54808 | VX-407 | VX-407 is a first-in-class small molecule corrector that targets the underlying cause of ADPKD in a subset with responsive PKD1 mutations. |
M27926 | BPKDi | BPKDi is a potent bipyridyl PKD inhibitor with IC50s of 1 nM, 9 nM and 1 nM for PKD1, PKD2 and PKD3, respectively. BPKDi blocks signal-dependent phosphorylation and nuclear export of class IIa HDACs in cardiomyocytes. |
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