| Cat.No. | Name | Information |
|---|---|---|
| M21136 | ABD957 | ABD957 is a potent and selective covalent inhibitor of the ABHD17 family of depalmitoylases, inhibiting IC50 at an IC50 of 0.21 µM. ABD957 impaired N-Ras depalmitylation in AML cells, reducing N-Ras signaling and the growth of NRAS mutant AML cells. |
| M21099 | MAGLi 432 | MAGLi 432 is a novel, reversible inhibitor of monoacylglycerol lipase (MAGL). |
| M13413 | JNJ-42226314 | JNJ-42226314 is a competitive, highly selective and reversible inhibitor of non-covalent monoacylglycerol lipase (MAGL). The IC50s of JNJ-42226314 against human Hela cells, human PBMC, mouse brain and rat brain were 1.13 nM, 1.88 nM, 0.67 nM and 0.97 nM, respectively. |
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