| Cat.No. | Name | Information |
|---|---|---|
| M14457 | FX-11 | FX-11 (LDHA Inhibitor FX11) is a potent lactate dehydrogenase A (LDHA) inhibitor with an IC50 of 23.3 μM for HeLa cell and a Ki value of 8 μM. FX-11 can reduce ATP levels, induce oxidative stress and ROS production, and cause cell death. |
| M10771 | (R)-GNE-140 | (R)-GNE-140 is a selective inhibitor of LDHA and LDHB with IC50 of 3 nM and 5 nM, respectively. (R)-GNE-140 is 18 times more potent than its S-type isomer. |
| M10743 | GNE-140 racemate | GNE-140 racemate is a racemic mixture of (R)-GNE-140 and (S)-GNE-140. GNE-140 racemate is also a potent lactate dehydrogenase A (LDHA) inhibitor. |
| M9849 | AZ-33 | AZ-33 (LDHA-IN-4) is a potent lactate dehydrogenase A (LDHA) inhibitor with IC50 of 0.5 μM. |
| M8543 | NHI-2 | NHI-2 is an inihbitor of Lactate dehydrogenase-A (LDH-A, LDHA), a key enzyme necessary to sustain glycolysis, the major pathway used by many cancer cells for cell growth and proliferation (the Warburg effect). |
| M6771 | GSK2837808A | GSK2837808A is a potent, selective lactate dehydrogenase A (LDHA) inhibitor with IC50s of 2.6 and 43 nM for hLDHA and hLDHB, respectively. |
| M6743 | Galloflavin | Galloflavin is a lactate dehydrogenase inhibitor; impairs aerobic glycolysis. |
| M42453 | Nedosiran sodium | Nedosiran sodium is a GalNAc-dsRNA conjugate designed to inhibit production of the hepatic lactate dehydrogenase (LDH) enzyme. |
| M31418 | MS6105 | MS6105 is an LDH protein hydrolysis-targeted chimera (PROTAC) with anticancer activity for studies related to pancreatic cancer. |
| M31417 | CHK-336 | CHK-336 is an inhibitor of the lactate dehydrogenase LDHA and can be used in studies related to primary hyperoxaluria. |
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