Interferon-α/β/γ Interferon-α/β/γ

Inhibitor/Activator

Cat.No.	Name	Information
M30500	RO8191	RO8191 (CDM-3008), an imidazonaphthyridine compound, is an orally active and potent interferon (IFN) receptor agonist. RO8191 directly binds to IFNα/β receptor 2 (IFNAR2) and activates IFN-stimulated genes (ISGs) expression and JAK/STAT phosphorylation. RO8191 shows antiviral activity against both HCV and EMCV with an IC50 of 200 nM for HCV replicon. RO8191 is a cccDNA modulator (CDM) through interferon-like activity and has anti-HBV activity.
M14089	IFN alpha-IFNAR-IN-1 hydrochloride	IFN alpha-IFNAR-IN-1 hydrochloride is a nonpeptidic, low-molecular-weight inhibitor of the interaction between IFN-α and IFNAR; inhibit MVA-induced IFN-α responses by BM-pDCs (IC50=2-8 uM).
M41988	IFN-γ Antagonist 1	IFN-γ Antagonist 1 (AYCRDGKIGPPKLDIRKEEKQI) is an antagonist of interferon γ (IFN γ).
M41987	IFN-γ Antagonist 1 acetate	IFN-γ Antagonist 1 (AYCRDGKIGPPKLDIRKEEKQI) acetate is an antagonist of interferon γ (IFN γ).
M41348	Delmitide acetate	Delmitide (RDP58) acetate is an orally active d-isomer decapeptide with potent anti-inflammatory activity.