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Integrin Integrin

Cat.No.  Name Information
M8975 CWHM-12 CWHM-12 is a potent inhibitor of αV integrins with IC50 values of 0.2, 0.8, 1.5, and 1.8 nM for αvβ8, αvβ3, αvβ6, and αvβ1, respectively.
M9173 Cilengitide trifluoroacetate Cilengitide is a potent integrin inhibitor for αvβ3 and αvβ5 receptor with IC50 of 4.1 nM, 79 nM in cell-free assays respectively.
M2042 Cilengitide Cilengitide (EMD 121974, NSC 707544) is a selective inhibitor of αvβ3 integrin and αvβ5 integrin with IC50 of 1 nM and 140 nM, respectively.
M53333 Cyclo(Gly-Arg-Gly-Asp-Ser-Pro) Cyclo(Gly-Arg-Gly-Asp-Ser-Pro) (c(GRGDSP)) is an RGD-containing inhibitory peptide.
M53332 Cyclo(Arg-Gly-Asp-D-Phe-Val) Cyclo(Arg-Gly-Asp-D-Phe-Val) is an integrin αvβ3 inhibitor.
M53331 Cyclo(Ala-Arg-Gly-Asp-Mamb) Cyclo(Ala-Arg-Gly-Asp-Mamb) is a selective RGD peptide antagonist and has the potential for Pulmonary arterial hypertension Research.
M53330 Eptifibatide monoacetate Eptifibatide monoacetate is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity.
M53329 cRGDfK-thioacetyl ester cRGDfK-thioacetyl ester is a bioactive polypeptide molecule.
M53328 Lys-Gln-Ala-Gly-Asp-Val Lys-Gln-Ala-Gly-Asp-Val (KQAGDV) is the six most carboxyl-terminal amino acids in the fibrinogen γ-chain sequence.
M53327 Galacto-RGD Galacto-RGD is an RGD analogue that can be coupled with the radioactive isotope 18F and used as an integrin α₅β₃ selective tracer.
M53326 RGDSPASSKP RGDSPASSKP is a RGDS-containing fibronectin decapeptide.
M53325 Batifiban Batifiban, a cyclic peptide, is a platelet glycoprotein GPⅡb/Ⅲa antagonist, and inhibits platelet aggregation.
M53324 EILEVPST EILEVPST is a recombinant human fibronectinderived low-molecular-weight peptide fragment.
M53323 LDV-FITC LDV-FITC, a fluorescent peptide, is a FITC-conjugated LDV peptide.
M53322 REDV REDV is the minimal active sequence within the CS5 site of the alternatively spliced type III connecting segment (IIICS) region of fibronectin.
M53321 mP6 mP6 (Myr-FEEERA-OH) is a myristoylated peptide.
M45159 SGN-B6A SGN-B6A is an integrin-targeted ADC that selectively targets solid tumors by recognizing ITGB6.
M45158 Alintegimod Alintegimod is an orally active variant activator of integrins αLβ2 and α4β1 that enhances T cell activation and adhesion.
M45157 OS2966 OS2966 is a first-in-class (first-in-class) neutralizing anti-CD29 monoclonal antibody that selectively modulates CD29 (integrin b1 subunit) and can be used in glioblastoma-related studies.
M45156 JSM-6427 JSM-6427 is an integrin α5β1 antagonist.
M45155 MORF-057 MORF-057 is an oral small molecule α4β7 integrin (integrin) inhibitor that can be used in studies related to ulcerative colitis (UC).
M45154 PN-943 PN-943 is a potentially first-in-class, orally active, specific α4β7 integrin antagonist peptide for studies related to inflammatory bowel disease (IBD).
M45153 PLN-1474 PLN-1474 is an orally active, selective ανβ1 integrin inhibitor with an IC50 value of <50 nM.PLN-1474 significantly reduces hepatic pSMAD3/SMAD3 levels, hepatic collagen gene expression, and hepatic OHP concentration in a mouse model of liver fibrosis. It can be used in studies related to liver cirrhosis and fibrosis.




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