Cat.No. | Name | Information |
---|---|---|
M8975 | CWHM-12 | CWHM-12 is a potent inhibitor of αV integrins with IC50 values of 0.2, 0.8, 1.5, and 1.8 nM for αvβ8, αvβ3, αvβ6, and αvβ1, respectively. |
M9173 | Cilengitide trifluoroacetate | Cilengitide is a potent integrin inhibitor for αvβ3 and αvβ5 receptor with IC50 of 4.1 nM, 79 nM in cell-free assays respectively. |
M2042 | Cilengitide | Cilengitide (EMD 121974, NSC 707544) is a selective inhibitor of αvβ3 integrin and αvβ5 integrin with IC50 of 1 nM and 140 nM, respectively. |
M53333 | Cyclo(Gly-Arg-Gly-Asp-Ser-Pro) | Cyclo(Gly-Arg-Gly-Asp-Ser-Pro) (c(GRGDSP)) is an RGD-containing inhibitory peptide. |
M53332 | Cyclo(Arg-Gly-Asp-D-Phe-Val) | Cyclo(Arg-Gly-Asp-D-Phe-Val) is an integrin αvβ3 inhibitor. |
M53331 | Cyclo(Ala-Arg-Gly-Asp-Mamb) | Cyclo(Ala-Arg-Gly-Asp-Mamb) is a selective RGD peptide antagonist and has the potential for Pulmonary arterial hypertension Research. |
M53330 | Eptifibatide monoacetate | Eptifibatide monoacetate is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity. |
M53329 | cRGDfK-thioacetyl ester | cRGDfK-thioacetyl ester is a bioactive polypeptide molecule. |
M53328 | Lys-Gln-Ala-Gly-Asp-Val | Lys-Gln-Ala-Gly-Asp-Val (KQAGDV) is the six most carboxyl-terminal amino acids in the fibrinogen γ-chain sequence. |
M53327 | Galacto-RGD | Galacto-RGD is an RGD analogue that can be coupled with the radioactive isotope 18F and used as an integrin α₅β₃ selective tracer. |
M53326 | RGDSPASSKP | RGDSPASSKP is a RGDS-containing fibronectin decapeptide. |
M53325 | Batifiban | Batifiban, a cyclic peptide, is a platelet glycoprotein GPⅡb/Ⅲa antagonist, and inhibits platelet aggregation. |
M53324 | EILEVPST | EILEVPST is a recombinant human fibronectinderived low-molecular-weight peptide fragment. |
M53323 | LDV-FITC | LDV-FITC, a fluorescent peptide, is a FITC-conjugated LDV peptide. |
M53322 | REDV | REDV is the minimal active sequence within the CS5 site of the alternatively spliced type III connecting segment (IIICS) region of fibronectin. |
M53321 | mP6 | mP6 (Myr-FEEERA-OH) is a myristoylated peptide. |
M45159 | SGN-B6A | SGN-B6A is an integrin-targeted ADC that selectively targets solid tumors by recognizing ITGB6. |
M45158 | Alintegimod | Alintegimod is an orally active variant activator of integrins αLβ2 and α4β1 that enhances T cell activation and adhesion. |
M45157 | OS2966 | OS2966 is a first-in-class (first-in-class) neutralizing anti-CD29 monoclonal antibody that selectively modulates CD29 (integrin b1 subunit) and can be used in glioblastoma-related studies. |
M45156 | JSM-6427 | JSM-6427 is an integrin α5β1 antagonist. |
M45155 | MORF-057 | MORF-057 is an oral small molecule α4β7 integrin (integrin) inhibitor that can be used in studies related to ulcerative colitis (UC). |
M45154 | PN-943 | PN-943 is a potentially first-in-class, orally active, specific α4β7 integrin antagonist peptide for studies related to inflammatory bowel disease (IBD). |
M45153 | PLN-1474 | PLN-1474 is an orally active, selective ανβ1 integrin inhibitor with an IC50 value of <50 nM.PLN-1474 significantly reduces hepatic pSMAD3/SMAD3 levels, hepatic collagen gene expression, and hepatic OHP concentration in a mouse model of liver fibrosis. It can be used in studies related to liver cirrhosis and fibrosis. |
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