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Histone Methyltransferase Histone methyltransferase

Cat.No.  Name Information
M2358 3-Deazaneplanocin A 3-deazaneplanocin A (DZNeP), an analog of adenosine, is a competitive inhibitor of S-adenosylhomocysteine hydrolase with Ki of 50 pM.
M56064 TM2-115  TM2-115 inhibits malaria parasite histone methyltransferases, resulting in rapid and irreversible parasite death.
M56063 (R)-HH2853  (R)-HH2853 is a mutant EZH2 inhibitor with an IC50 of <100 nM for EZH2-Y641F.
M56062 G9a-IN-1  G9a-IN-1 is a G9a protein inhibitor.
M56061 OTS193320  OTS193320, a imidazo[1,2-a]pyridine compound, is a SUV39H2 methyltransferase activity inhibitor.
M56060 PRMT5-IN-9  PRMT5-IN-9 is a novel PRMT5 inhibitor for researching cancer, with an IC50 of 0.01 μM.
M56059 UNC8153 TFA  UNC8153 TFA is a potent and selective nuclear receptor-binding SET domain-containing 2 (NSD2)-targeted degrader with a Kd of 24 nM.
M56058 EED ligand 1  EED ligand 1 is a diverse, potent, and efficacious inhibitor that target the EED subunit of the polycomb repressive complex 2 (PRC2) methyltransferase.
M56057 CM-579 trihydrochloride  CM-579 trihydrochloride is a first-in-class reversible, dual inhibitor of G9a and DNMT, with IC50 values of 16 nM, 32 nM for G9a and DNMT, respectively.
M56056 EPZ011989 hydrochloride  EPZ011989 hydrochloride is a potent and orally active Zeste Homolog 2 (EZH2) inhibitor, with a Ki value of <3 nM.
M53317 SAH-EZH2 SAH-EZH2, a stable EZH2 α-helical peptide, is an EZH2/EED interaction inhibitor.
M53316 UNC4976 UNC4976 is a positive allosteric modulator (PAM) peptidomimetic of CBX7 chromodomain binding to nucleic acids.
M53315 C21 C21 is a potent, irreversible, and selective PRMT1 inhibitor with an IC50 of 1.8 μM.
M41699 EZH2-IN-15 EZH2-IN-15 (SHR2554) is a EZH2 inhibitor.
M41698 NSD-IN-2 NSD-IN-2 is a potent and irreversible NSD1 inhibitor.
M41697 MS9715 MS9715 is a potent and seletive NSD3-targeting PROTAC.
M41696 NSD2-IN-4 NSD2-IN-4 is a potent and selective NSD2-SET inhibitor.
M41695 PRMT4-IN-1 PRMT4-IN-1 is a selective inhibitor of PRMT4 (IC50=3.2 nM).
M41694 WM-662 WM-662 is a WDR5-MYC interaction inhibitor, with an IC50 of 18 μM.
M41693 PRMT5-IN-25 PRMT5-IN-25 is a potent PRMT5 inhibitor with an Ki value of 0.06 nM.
M41692 UNC7096 UNC7096 is a potent and selective NSD2-PWWP1 degrader with a Kd of 46 nM.




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