Cat.No. | Name | Information |
---|---|---|
M2358 | 3-Deazaneplanocin A | 3-deazaneplanocin A (DZNeP), an analog of adenosine, is a competitive inhibitor of S-adenosylhomocysteine hydrolase with Ki of 50 pM. |
M56064 | TM2-115 | TM2-115 inhibits malaria parasite histone methyltransferases, resulting in rapid and irreversible parasite death. |
M56063 | (R)-HH2853 | (R)-HH2853 is a mutant EZH2 inhibitor with an IC50 of <100 nM for EZH2-Y641F. |
M56062 | G9a-IN-1 | G9a-IN-1 is a G9a protein inhibitor. |
M56061 | OTS193320 | OTS193320, a imidazo[1,2-a]pyridine compound, is a SUV39H2 methyltransferase activity inhibitor. |
M56060 | PRMT5-IN-9 | PRMT5-IN-9 is a novel PRMT5 inhibitor for researching cancer, with an IC50 of 0.01 μM. |
M56059 | UNC8153 TFA | UNC8153 TFA is a potent and selective nuclear receptor-binding SET domain-containing 2 (NSD2)-targeted degrader with a Kd of 24 nM. |
M56058 | EED ligand 1 | EED ligand 1 is a diverse, potent, and efficacious inhibitor that target the EED subunit of the polycomb repressive complex 2 (PRC2) methyltransferase. |
M56057 | CM-579 trihydrochloride | CM-579 trihydrochloride is a first-in-class reversible, dual inhibitor of G9a and DNMT, with IC50 values of 16 nM, 32 nM for G9a and DNMT, respectively. |
M56056 | EPZ011989 hydrochloride | EPZ011989 hydrochloride is a potent and orally active Zeste Homolog 2 (EZH2) inhibitor, with a Ki value of <3 nM. |
M53317 | SAH-EZH2 | SAH-EZH2, a stable EZH2 α-helical peptide, is an EZH2/EED interaction inhibitor. |
M53316 | UNC4976 | UNC4976 is a positive allosteric modulator (PAM) peptidomimetic of CBX7 chromodomain binding to nucleic acids. |
M53315 | C21 | C21 is a potent, irreversible, and selective PRMT1 inhibitor with an IC50 of 1.8 μM. |
M41699 | EZH2-IN-15 | EZH2-IN-15 (SHR2554) is a EZH2 inhibitor. |
M41698 | NSD-IN-2 | NSD-IN-2 is a potent and irreversible NSD1 inhibitor. |
M41697 | MS9715 | MS9715 is a potent and seletive NSD3-targeting PROTAC. |
M41696 | NSD2-IN-4 | NSD2-IN-4 is a potent and selective NSD2-SET inhibitor. |
M41695 | PRMT4-IN-1 | PRMT4-IN-1 is a selective inhibitor of PRMT4 (IC50=3.2 nM). |
M41694 | WM-662 | WM-662 is a WDR5-MYC interaction inhibitor, with an IC50 of 18 μM. |
M41693 | PRMT5-IN-25 | PRMT5-IN-25 is a potent PRMT5 inhibitor with an Ki value of 0.06 nM. |
M41692 | UNC7096 | UNC7096 is a potent and selective NSD2-PWWP1 degrader with a Kd of 46 nM. |
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