| Cat.No. | Name | Information |
|---|---|---|
| M53113 | Guanylin(human) | Guanylin(human), a 15-amino acid peptide, is an endogenous intestinal guanylate cyclase activator. |
| M49830 | Plecanatide acetate | Plecanatide acetate is an analog of urinary guanosine protein and an orally active guanylate cyclase-C (GC-C) receptor agonist with an EC50 value of 190 nM in T84 cells.Additionally, Plecanatide acetate has been shown to have anti-inflammatory activity and can be used in studies related to chronic idiopathic constipation. In addition, Plecanatide acetate has anti-inflammatory activity and can be used in studies related to chronic idiopathic constipation. |
| M21131 | Runcaciguat | Runcaciguat is an orally available soluble guanylate cyclase promoter that can be combined with selective partial adenosine A1 receptor agonists for the study of cardiovascular and renal disease. |
| M13989 | Cinaciguat | Cinaciguat is an activator of guanylate cyclase (sGC), and used for acute decompensated heart failure. |
| M10118 | Vericiguat | Vericiguat is a potent and orally available stimulator of guanylate cyclase (sGC). |
| M10103 | Plecanatide | Plecanatide is a structural analog of human uroguanylin, and similarly to uroguanylin, plecanatide functions as a guanylate cyclase-C (GC-C) agonist. |
| M8336 | Ebselen Oxide | Ebselen oxide is a potent inhibitor of a-Methylacyl coenzyme A racemase (AMACR). |
| M7526 | Linaclotide | Linaclotide is a potent and selective guanylate cyclase C agonist; developed for the treatment of constipation-predominant irritable bowel syndrome (IBS-C) and chronic constipation. |
| M6490 | BAY 41-8543 | BAY 41-8543 is a guanylyl cyclase (sGC) stimulator. |
| M6489 | BAY 41-2272 | BAY 41-2272 is a soluble guanylyl cyclase (sGC) activator. |
| M6365 | A 350619 hydrochloride | A 350619 hydrochloride is a soluble guanylyl cyclase (sGC) activator. |
| M5932 | Riociguat (BAY 63-2521) | Riociguat (BAY 63-2521) is an oral soluble guanylate cyclase (GC) stimulator, used in the research of ipulmonary hypertension. |
| M56208 | BAY-747 | BAY-747 (BAY 1165747) is an orally active and brain-penetrant stimulator of soluble guanylate cyclase (sGC). |
| M56207 | MCUF-651 | MCUF-651 is an orally active guanylyl cyclase A receptor (GC-A) positive allosteric modulator (PAM) (KD: 397 nM ). |
| M56206 | Zagociguat | Zagociguat is the stimulator of soluble guanylate cyclase. |
| M56205 | 2-Chloro-ATP | 2-Chloro-ATP is a soluble guanylate cyclase inhibitor that increases intracellular calcium concentration at low concentrations through a mechanism independent of inositol phosphate production. |
| M56204 | CFM 1571 hydrochloride | CFM 1571 hydrochloride is the stimulator of the nitric oxide receptor, soluble guanylate cyclase (sGC) with an EC50 and IC50 of 5.49 μM and 2.84 μM, respectively. |
| M54169 | MM 419447 | MM 419447, a linaclotide metabolite, is a guanylate cyclase-C agonist. |
| M53112 | Cenderitide | Cenderitide is a potent agonist of particulate guanylyl cyclase receptor (pGC). |
| M53111 | Prepro-ANF (56-92), human | Prepro-ANF (56-92), human is a human atrial natriuretic factor precursor. |
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