Gli Gli

Cat.No.	Name	Information
M2448	GANT61	GANT61 is a Gli1 and Gli2 inhibitor targeting the Hedgehog/GLi pathway that inhibits GLI1- and GLI2-induced transcription with an IC50 of 5 μM. In addition, GANT61 selectively acts on the transcription of other pathways such as TNF and glucocorticoid receptor genes.
M1812	GANT58	GANT58 (NSC75503) is a potent GLI antagonist that inhibits GLI1-induced transcription with an IC50 of 5 μM.
M45319	GLI antagonist-1	GLI antagonist-1 is a potent GLI antagonist with an IC50 value of 1.1 µM. In addition, GLI antagonist-1 has antiproliferative activity by reducing GLI1 mRNA expression and dose-dependently inhibiting colony formation.
M45268	Glabrescione B	Glabrescione B is a selective GLI1 inhibitor that impairs Gli1 activity by interfering with Gli1-DNA interactions. In addition, Glabrescione B inhibits the growth of Hedgehog-dependent tumor cells and suppresses the self-renewal capacity and clonogenic ability of tumor-derived stem cells.