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Abmole Inhibitor Catalog 2017

Sirtuin Sirtuin

Inhibitors

Cat.No.  Name Information
M5265 Thiomyristoyl Thiomyristoyl is a potent and specific SIRT2 inhibitor with an IC50 of 28 nM. It inhibits SIRT1 with an IC50 value of 98 μM and does not inhibit SIRT3 even at 200 μM.
M4896 Nicotinamide Nicotinamide is an active component of coenzymes NAD and NADP, and also act as an inhibitor of sirtuins.
M4678 Fisetin Fisetin (Fustel) is a potent sirtuin activating compound (STAC) and an agent that modulates sirtuins.
M3010 Sirtinol Sirtinol is a specific SIRT1 and SIRT2 inhibitor with IC50 of 131 μM and 38 μM, respectively.
M2267 Resveratrol Resveratrol is a phytoestrogen with antitumor, antioxidant, antiplatelet, anti-inflammatory and antifungal effects.
M1824 SRT1720 Hydrochloride SRT1720 Hydrochloride is a selective small molecule activator of SIRT1 that is 1,000-fold more potent than resveratrol (EC1.5 = 0.16 versus 46.2 µM, respectively).


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