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Serine/Threonine Protease Serine/Threonine Protease


Cat.No.  Name Information
M14534 WNK-IN-11 WNK-IN-11 is an allosteric With-No-Lysine (WNK) kinase inhibitor, with an IC50 of 4 nM for WNK1.
M14533 IPR-803 IPR-803 is a potent inhibitor of the uPAR•uPA protein-protein interaction (PPI). IPR-803 binds directly to uPAR with sub-micromolar affinity. IPR-803 displays anti-tumor activity.
M14532 Avoralstat Avoralstat (BCX4161), a potent and orally active plasma kallikrein (PKK) inhibitor, is used for hereditary angioedema research.
M11345 Inclisiran Inclisiran (ALN-PCSSC) is a double-stranded small interfering RNA (siRNA) molecule that inhibits the transcription of PCSK-9. Inclisiran can be used in hyperlipidemia and cardiovascular disease (CVD) studies.
M11343 Pinostrobin Pinostrobin is a flavonoid found in many plants and has antioxidant, anti-inflammatory, anticancer and neuroprotective properties. Pinostrobin is an effective INHIBITOR of PCSK9, which can inhibit the catalytic activity of PCSK9. Pinostrobin is a promising agent for cholesterol regulation and lipid management.
M11214 WNK463 WNK463 is an oral WNK kinase inhibitor for WNK1, WNK2, WNK3, and WNK4 IC50 The values are 5 nM, 1 nM, 6 nM, and 9 nM, respectively.
M10641 FOY-251 mesylate FOY-251 mesylate is a metabolite of Camostat that acts as a pollen protease inhibitor for prevention and control of allergies.
M10598 SPHINX31 SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1) with IC50 of 5.9 nM. SPHINX31 inhibits phosphorylation of serine/arginine-rich splicing factor 1 (SRSF1).
M10198 Zabedosertib Zabedosertib is a serine/ threonine kinase inhibitor.
M9648 Empesertib Empesertib (BAY1161909) is an orally bioavailable, selective inhibitor of the serine/threonine monopolar spindle 1 (Mps1) kinase (IC50 of < 1 nM), with potential antineoplastic activity.

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