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Immunology/Inflammation Immunology/Inflammation

Inhibitors

Cat.No.  Name Information
M4614 Orientin Orientin
M9524 Lipopolysaccharides Lipopolysaccharides (LPS) is an endotoxin derived from the outer leaflet of the outer membrane of Gram-negative bacteria. This product is derived from Escherichia coli O55:B5.
M6223 Tocilizumab Tocilizumab is a humanized monoclonal antibody that binds to the interleukin-6 receptor, MW: 148 KD.
M21029 MRE-269(ACT-333679) MRE-269(ACT-333679) is a prostaglandin I2 (IP) receptor agonist with a binding affinity for the human IP receptor that is 130-fold greater than that for other human prostanoid receptor.
M21012 Loxoprofen Sodium Loxoprofen Sodium is a nonsteroidal anti-inflammatory drug (NSAID) in the propionic acid derivatives group
M20998 PMX-53 PMX-53 is a potent CD88 (C5aR) antagonist that inhibits C5a-induced neutrophil myeloperoxidase release and chemotaxis with IC50 values of 22 nM and 75 nM, respectively. PMX-53 is also a low-affinity MrgX2 agonist that stimulates MrgX2-mediated mast cell degranulation. PMX-53 has anti-inflammatory, anti-cancer and anti-atherosclerotic effects.
M20985 Perflubron Perflubron (1-Bromoperfluorooctane, Perfluorooctyl bromide, Oxygent, PFOB) exhibits anti-inflammatory activity thus decreases cytokine production in human alveolar macrophages. Perflubron also attenuates oxidative damage to both biological and nonbiological systems which is independent of its anti-inflammatory properties.
M20970 Adelmidrol Adelmidrol is an analogue of palmitoylethanolamide (PEA) with anti-inflammatory activities.
M20960 Tinoridine hydrochloride Tinoridine hydrochloride is a non-steroidal anti-inflammatory drug with a potent antiperoxidative activity.
M20958 Talniflumate Talniflumate is an anti-inflammatory molecule studied and used as a mucin regulator in the treatment of cystic fibrosis, chronic obstructive pulmonary disease (COPD) and asthma.
M20939 Diclofenac Epolamine Diclofenac Epolamine is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions.
M20931 Benzalkonium chloride Benzalkonium chloride is a cationic surface-acting agent containing the quaternary ammonium group
M20675 Etofenamate Etofenamate is a nonsteroidal anti-inflammatory drug (NSAID) used for the treatment of joint and muscular pain.
M20667 Anisodamine Hydrobromide Anisodamine is a naturally occurring atropine derivative and exhibits anti-inflammatory activity. It also inhibits α1-adrenergic receptors and muscarinic acetylcholine receptors (mAChRs).
M20612 Cl-amidine Cl-amidine is an irreversible pan-peptidylarginine deiminase (PAD) inhibitor with IC50 values of 5.9 ± 0.3 μM, 0.8 ± 0.3 μM, 6.2 ± 1.0 μM for PAD4, PAD1 and PAD3, respectively.
M20567 Salicylamide Salicylamide is a non-prescription drug with analgesic and antipyretic properties.
M20561 Picolinic acid (PCL 016) PCL016 is a pyridine carboxylate metabolite of tryptophan and acts as an anti-infective and immunomodulator. It acts by binding with the zinc associated with zinc finger proteins to alter their structure and inhibit function.
M20544 Trans-Tranilast Trans-Tranilast is an antiallergic drug, used to treat bronchial asthma, allergic rhinitis and atopic dermatitis.
M20536 Setipiprant (ACT-129968, KYTH-105) Setipiprant(ACT-129968, KYTH-105) is a selective, orally available antagonist of the prostaglandin D2 receptor 2 (DP2) that that has been shown to have greater specificity for DP2 (CRTH2) than for DP1.
M20448 Actarit Actarit is an orally active immunomodulator used in the treatment of rheumatoid arthritis.
M20433 Tolmetin Tolmetin is a nonsteroidal anti-inflammatory drug of the heterocyclic acetic acid derivative class and also exhibits analgesic and antipyretic activity.
M20432 5-Acetylsalicylic acid 5-Acetylsalicylic acid, also known as Mesalazine or Mesalamine, is an aminosalicylate anti-inflammatory drug used to treat inflammatory bowel disease.
M20418 Dehydroandrographolide Succinate Potasium Salt Dehydroandrographolide Succinate (DAS), extracted from herbal medicine Andrographis paniculata (Burm f) Nees, is widely used for the treatment of viral pneumonia and viral upper respiratory tract infections because of its immunostimulatory, anti-infective and anti-inflammatory effect.



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