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Abmole Inhibitor Catalog 2017

Immunology/Inflammation Immunology/Inflammation


Cat.No.  Name Information
M10093 α-Galactosyl Ceramide α-Galactosyl Ceramide is a potent NKT cell stimulator and selective CD1d ligand.
M9509 NS-3-008 hydrochloride NS-3-008 hydrochloride is an orally active transcriptional inhibitor of G0/G1 switch 2 (G0s2) with an IC50 of 2.25 μM.
M9358 ITE ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR), which directly binding to AHR with a Ki of 3 nM.
M9298 AX-024 hydrochloride AX-024 hydrochloride is a potent cytokine release inhibitor, inhibits the production of interferon-γ (IFN-γ), interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), IL-10 and IL-17A.
M9122 Tormentic Acid Tormentic Acid is a natural anti-inflammatory agent which inhibits production of tumor necrosis factor‑α (TNF‑α), interleukin 6 (IL‑6), and IL‑1β.
M9117 W-54011 W-54011 is a potent, specific, and orally active CD88 (C5a receptor) antagonist, which inhibits the binding of 125I-labeled C5a to human neutrophils with a Ki value of 2.2 nM.
M8247 AUDA AUDA is a potent inhibitor of soluble epoxide hydrolase (sEH) with IC50 of 18 nM and 69 nM for the mouse sEH and human sEH, respectively. AUDA has anti-inflammatory activity that reduces the protein expression of MMP-9, IL-1β, TNF-α and TGF-β.
M6223 Tocilizumab Tocilizumab is a humanized monoclonal antibody that binds to the interleukin-6 receptor, MW: 148 KD.
M6219 Rituximab Rituximab is a chimeric anti-CD20 mAb that binds the CD20 antigen on B cells with a binding affinity of 5 nM, MW: 143.86 KD.
M4877 Karminomitsin Karminomitsin is a very toxic anthracycline-type antineoplastic related to DAUNORUBICIN, obtained from Actinomadura carminata.
M4825 SKQ1  SKQ1 is a potent mitochondria-targeted antioxidant.
M4791 Tussilagone Tussilagone is a major active component in Tussilago farfara, has anti-inflammatory effect.
M4790 β-demonic-acid β-demonic-acid exhibits anti-inflammatory effects.
M4750 Echinocystic-acid Echinocystic-acid
M4724 Leonurine hydrochloride Leonurine hydrochloride
M4704 Diosgenin-glucoside Diosgenin-glucoside is a saponin compound extracted from Tritulus terrestris L., protects against spinal cord injury by regulating autophagy and alleviating apoptosis.
M4686 Eriodictyol Eriodictyol
M4614 Orientin Orientin
M4389 Carnosol Carnosol is a phenolic diterpene with antioxidant and anticarcinogenic activities.
M4139 Salvianolic-acid-A Salvianolic-acid-A
M3998 Rhein Rhein, also known as cassic acid, is a substance in the anthraquinone group obtained from rhubarb.
M3634 TAPI-1 TAPI-1 is an ADAM17/TACE inhibitor that blocks shedding of cytokine receptors with IC50 value of 8.09 microM.
M3468 Methylprednisolone Methylprednisolone is a synthetic corticosteroid with anti-inflammatory and immunomodulating properties.
M3416 Mycophenolic acid Mycophenolic acid is an immunosuppressant agent used to prevent rejection in organ transplantation.
M3297 Meloxicam Meloxicam (Mobic) is a nonsteroidal anti-inflammatory agent with analgesic and fever reducer effects.
M2221 Pimecrolimus Pimecrolimus is an immunomodulating agent used in the treatment of atopic dermatitis.
M2098 Bindarit Bindarit is a specific anti-inflammatory small molecule inhibitor of MCP-1 production.
M1831 Cyclosporine A Cyclosporine A is a powerful immunosuppressive agent that inhibits the T-cell receptor signal transduction pathway.
M1803 Laquinimod Laquinimod (ABR-215062) is a new orally active immunoregulator effectively inhibits development and relapses of experimental autoimmune encephalomyelitis.

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