Inhibitors
Cat.No. | Name | Information |
---|---|---|
M7527 | Gilteritinib | Gilteritinib is a potent FLT3/AXL inhibitor with IC50 of 0.29 nM/0.73 nM, respectively. |
M5311 | AMG 925 | AMG 925 is a potent and orally bioavailable dual FLT3/CDK4 inhibitor with IC50 of 1 nM and 3 nM, respectively. |
M5142 | G-749 | G-749 is a novel and potent FLT3 inhibitor with IC50 of 0.4 nM, 0.6 nM and 1 nM for FLT3 (WT), FLT3 (D835Y), and Mer, respectively, showing lower potency against other tyrosine kinases. |
M5026 | UNC-2025 | UNC-2025 is a potent and orally bioavailable dual MER/FLT3 inhibitor with IC50 of 0.74 nM and 0.8 nM, respectively, about 20-fold selectivity over Axl and Tyro3. |
M3800 | CGP52421 | CGP52421 is a FLT3 inhibitor, which is also an metabolite of midostaurin (PKC412). |
M3053 | TCS 359 | TCS 359 is a potent FLT3 inhibitor with IC50 of 42 nM. |
M1828 | Tandutinib | Tandutinib (MLN518), previously known as CT53518, is an orally active multitargeted tyrosine kinase inhibitor of FLT3, PDGFR and c-Kit. |
M1815 | KW-2449 | KW-2449 is a novel multitargeted kinase inhibitor of FLT3, ABL and Aurora kinase with IC50 values of 6.6 nM, 14 nM and 48 nM. |
M1641 | AC220 | AC220 (Quizartinib) is a uniquely potent and selective FLT3 inhibitor. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2020 AbMole BioScience. All Rights Reserved.