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Inhibitors
| Cat.No. | Name | Information |
|---|---|---|
| M10244 | Imidazole ketone erastin | Imidazole ketone erastin (IKE) is an inducer of ferroptosis, and it is also a potent, selective, and metabolically stable inhibitor of the cystine-glutamate antiporter, system Xc-. |
| M9404 | UAMC-3203 hydrochloride | UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor, with an IC50 of 12 nM. |
| M9060 | RSL3 | RSL3 is an inhibitor of the glutathione (GSH) peroxidase 4, which can inhibit the cysteine/glutamate amino acid transporter system. |
| M8531 | Liproxstatin-1 | Liproxstatin-1 is a potent inhibitor of ferroptosis, a non-apoptotic form of cell death characterized by iron-dependent accumulation of lethal lipid reactive oxygen species (ROS). |
| M7504 | CIL56 (CA3) | CIL56 (CA3) is a potent and selective ferroptosis inducer, it has potent inhibitory effects on YAP1/Tead transcriptional activity and primarily targets YAP1 high and therapy-resistant esophageal adenocarcinoma cells endowed with CSC properties. |
| M6731 | FIN56 | FIN56 is a ferroptosis activator. |
| M5558 | Deferoxamine mesylate | Deferoxamine mesylate as a chelating agent used to remove excess iron from the body. |
| M3400 | Idebenone | Idebenone is a synthetic analog of coenzyme Q10 (CoQ10) and a brain stimulant. |
| M2698 | Ferrostatin-1 | Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of ferroptosis with EC50 of 60 nM. |
| M2679 | Erastin | Erastin is a ferroptosis activator by acting on mitochondrial VDAC, exhibiting selectivity for tumor cells bearing oncogenic RAS. *The compound is unstable in solutions, freshly prepared is recommended |
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