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Ethylenediaminetetraacetic acid trisodium salt

Cat. No. M13546
Ethylenediaminetetraacetic acid trisodium salt Structure
Synonym:

EDTA trisodium salt; Trisodium EDTA

Size Price Availability Quantity
500mg USD 50  USD50 In stock
1g USD 60  USD60 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Ethylenediaminetetraacetic acid trisodium salt (EDTA trisodium salt) is used to bind metal ions in the practice of chelation therapy, for treating mercury and lead poisoning, used in a similar manner to remove excess iron from the body, for treating the complication of repeated blood transfusions, as would be applied to treat thalassaemia.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 358.19
Formula
CAS Number 150-38-9
Purity >99%
Solubility Water 50 mg/mL
Storage 2-8°C, dry, sealed
References

[1] Ning Yang, et al. Langmuir. Preparation of CaF 2 Microspheres with Nanopetals for Water Vapor Adsorption

[2] Palash Kumar Manna, et al. Dalton Trans. EDTA-Na 3 functionalized Fe 3 O 4 nanoparticles: grafting density control for MRSA eradication

[3] Da Huo, et al. Nano Lett. Seed-Mediated Growth of Au Nanospheres into Hexagonal Stars and the Emergence of a Hexagonal Close-Packed Phase

[4] Giuseppe Lippi, et al. Clin Chem Lab Med. EDTA-dependent pseudothrombocytopenia: further insights and recommendations for prevention of a clinically threatening artifact

[5] Rebecca S Lanigan, et al. Int J Toxicol. Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA

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Keywords: Ethylenediaminetetraacetic acid trisodium salt, EDTA trisodium salt; Trisodium EDTA supplier, Ferroptosis, inhibitors

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