Catalog

Cathepsin Cathepsin

Inhibitors

Cat.No.	Name	Information
M10280	L006235	L006235 (L235) is a potent, reversible cathepsin K inhibitor (IC50 = 0.25 nM) that displays > 4000-fold selectivity over cathepsins B, L and S.
M9353	N-Ethylmaleimide	N-Ethylmaleimide (NEM) is a cysteine protease inhibitor.
M6236	CA-074 Me	CA-074 Me is a membrane-permeable derivative of CA-074 and acts as an irreversible cathepsin B inhibitor.
M5288	UK-371804	UK-371804 is a potent and selective urokinase-type plasmogen activator (uPA) inhibitor with excellent enzyme potency (Ki=10 nM) and selectivity profile (4000-fold versus tPA and 2700-fold versus plasmin).
M5167	Calpeptin	Calpeptin is a potent, cell-permeable inhibitor of the Ca²⁺-dependent protease, calpain.
M3826	Papain	Papain is a cysteine protease of the peptidase C1 family.
M3636	Leupeptin hemisulfate	Leupeptin hemisulfate is a reversible inhibitor of trypsin-like and cysteine proteases such as calpain.
M2600	Balicatib	Balicatib is a potent and selective inhibitor of cathepsin K; 10-100-fold more potent in cell-based enzyme occupancy assays than against cathepsin B, L, and S.
M2376	Aloxistatin	Aloxistatin (E64d) is an irreversible and membrane-permeable cysteine protease inhibitor.
M1985	Odanacatib	Odanacatib (MK-0822) is an inhibitor of cathepsin K, an enzyme involved in bone resorption.