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Aloxistatin

Cat. No. M2376
Aloxistatin Structure
Synonym:

E64d

Size Price Availability Quantity
5mg USD 99  USD110 In stock
10mg USD 171  USD190 In stock
25mg USD 378  USD420 In stock
50mg USD 666  USD740 In stock
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Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

Aloxistatin (E64d) is an irreversible and membrane-permeable cysteine protease inhibitor.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 342.43
Formula C17H30N2O5
CAS Number 88321-09-9
Purity >98%
Solubility DMSO 48 mg/mL
Storage at -20°C
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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Aloxistatin, E64d supplier, Cathepsin, inhibitors

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