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  Catalog
Abmole Inhibitor Catalog 2017

Antifolate Antifolate

Inhibitors

Cat.No.  Name Information
M5866 Pemetrexed Disodium Hydrate Pemetrexed Disodium Hydrate is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM, respectively.
M3303 Pralatrexate Pralatrexate is an antifolate, and structurally a folate analog. Its IC50 is < 300 nM in some cell lines.
M3090 Trimethoprim Trimethoprim is a bacteriostatic antibiotic mainly used in the prophylaxis and treatment of urinary tract infections.
M2711 Folinic acid calcium salt Folinic acid is an adjuvant used in cancer chemotherapy involving the compound methotrexate.


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