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Abmole Inhibitor Catalog 2017

Antifolate Antifolate


Cat.No.  Name Information
M7108 Pemetrexed Pemetrexed is a thymidylate synthetase inhibitor, also inhibits dihydrofolate reductase, GARFT and AICART.
M5866 Pemetrexed Disodium Hydrate Pemetrexed Disodium Hydrate is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM, respectively.
M3303 Pralatrexate Pralatrexate is an antifolate, and structurally a folate analog. Its IC50 is < 300 nM in some cell lines.
M3090 Trimethoprim Trimethoprim is a bacteriostatic antibiotic mainly used in the prophylaxis and treatment of urinary tract infections.
M2711 Folinic acid calcium salt Folinic acid is an adjuvant used in cancer chemotherapy involving the compound methotrexate.
M2228 Abitrexate (Methotrexate) Abitrexate is an antimetabolite and antifolate agent with antineoplastic and immunosuppressant activities.

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