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Inhibitors
| Cat.No. | Name | Information |
|---|---|---|
| M9091 | A-779 | A-779 is a specific antagonist of G-protein coupled receptor (Mas receptor). |
| M9079 | Angiotensin-(1-7) | Angiotensin (1-7) is a synthetic heptapeptide identical to endogenous angiotensin-(1-7), inhibits purified canine angiotensin converting enzyme (ACE) activity with an IC50 of 0.65 μM. |
| M9056 | Losartan | Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM. |
| M8987 | EMA401 | EMA401 (also known as Olodanrigan and PD-126055) is a highly selective angiotensin AT2 antagonist. |
| M6240 | Angiotensin II human | Angiotensin II human is converted by Angiotensin I through removal of two C-terminal residues by the enzyme angiotensin-converting enzyme (ACE). Angiotensin II is mediated by AT1 and AT2 receptors, which are seven transmembrane glycoproteins with 30% sequence similarity. |
| M6025 | Tranilast | Tranilast is an antiallergic agent. |
| M5731 | LCZ696 | LCZ696, consisting of valsartan and sacubitril in 1:1 molar ratio, is an orally bioavailable, dual-acting angiotensin receptor-neprilysin inhibitor (ARNi) for hypertension and heart failure. Phase 3. |
| M3917 | PD 123319 | PD 123319 is a potent, selective AT2 angiotensin II receptor antagonist with IC50 of 34 nM. |
| M3511 | Olmesartan Medoxomil | Olmesartan Medoxomil is a compound which is hydrolyzed to olmesartan that is a selective AT1 subtype angiotensin II receptor antagonist. |
| M3507 | Valsartan | Valsartan is an angiotensin II receptor antagonist with IC50 of ranging from 39.5 to 116 μM. |
| M3265 | Olmesartan | Olmesartan is an angiotensin II receptor antagonist with an IC50 of 7.7 nM. |
| M2258 | Losartan potassium | Losartan potassium is a selective non-peptide angiotensin AT1 receptor antagonist. |
| M2164 | PD 123319 ditrifluoroacetate | PD 123319 ditrifluoroacetate is a potent, selective, non-peptide angiotensin AT2 receptor antagonist. |
| M2106 | Azilsartan | Azilsartan (TAK-536) is an angiotensin II type 1 (AT1) receptor antagonist with IC50 of 2.6 nM. |
| M2105 | Azilsartan medoxomil | Azilsartan medoxomil is an orally administered angiotensin II receptor type 1 antagonist. |
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