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AChR/AChE Acetylcholine Receptors/Acetylcholinesterase

Cat.No.  Name Information
M2489 Carbachol chloride Carbachol is a cholinomimetic compound that binds and activates the acetylcholine receptor.
M3470 Oxybutynin Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties.
M3190 PNU-282987 PNU-282987 is a highly selective α7 nAChR agonist with Ki of 27 nM.
M42646 SD-6 SD-6 is an orally active inhibitor of hAChE and hBChE with IC50 values of 0.907 µM and 1.579 µM, respectively.
M42645 Isogarcinol Isogarcinol (Cambogin) is a potent AChE and BChE inhibitor, with IC50 values of 1.13 and 8.30 μM, respectively.
M42644 hBChE-IN-2 hBChE-IN-2 is a butyrylcholinesterase (BChE) inhibitor (IC50 of 0.62 μM) and a cannabinoid receptor 2 (CB2R) agonist.
M42643 Octahydroaminoacridine Octahydroaminoacridine, a Tacrine analogue, is an acetylcholinesterse (AChE) and butyrylcholinesterase (BChE) inhibitor.
M42642 BChE-IN-17 BChE-IN-17 is a potent and selective BChE inhibitor with IC50s of 10.5 nM and 32.5 nM for eqBChE and hBChE, respectively.
M42641 AChE-IN-34 AChE-IN-34 is a potent and selective AChE inhibitor with an IC50 value of 3.98 µM with no significant inhibition against BChE.
M42640 BChE-IN-19 BChE-IN-19 is a para-substituted derivative of indone (7b) with inhibitory activity of butyryl cholinesterase (BChE) (IC50=0.04 μM).
M42639 Methyl ganoderate A acetonide Methyl ganoderate A acetonide, a lanostane triterpene, is a natural product that could be isolated from the fruiting bodies of Ganoderma lucidum.
M42638 hAChE/hBACE-1-IN-2 hAChE/hBACE-1-IN-2 is a potent, orally active, blood-brain barrier transboundary triple inhibitor of hAChE, hBChE, and HACE-1 with IC50s of 0.113 μM, 1.48 μM and 0.38 μM, respectively.
M42637 SB-1436 SB-1436 is an Cholinesterase (ChE) inhibitor, inhibits AChE, BChE and rHuAChE with IC50s of 0.176, 0.37 and 0.08 μM, respectively.
M42214 Tebanicline hydrochloride Tebanicline hydrochloride (Ebanicline hydrochloride) is a nAChR modulator with potent, orally effective analgesic activity.
M42213 CVN417 CVN417 is an orally active α6 subunit-containing nAChR antagonist, modulating phasic dopaminergic neurotransmission in an impulse-dependent manner.
M42212 Epiboxidine hydrochloride Epiboxidine hydrochloride is a potent and selective neural nAChR agonist with Kis of 0.46 nM and 1.2 nM for rat and human α4β2 nAChRs, respectively.
M42211 TC-1698 TC-1698 is a selective α7 nicotinic acetylcholine receptors agonist with EC50 value of 0.16 μM and 0.46 μM for monkey α7 nicotinic receptor and human α7 nicotinic receptor, respectively.
M41867 Oxyphenonium bromide Oxyphenonium bromide is an antiacetylcholine compound.
M41866 Nitrocaramiphen hydrochloride Nitrocaramiphen hydrochloride is a selective M1 receptor antagonist (Ki: 5.5 nM).
M41865 J-104129 J-104129 is a selective and orally active muscarinic M3 receptor antagonist (Ki = 4.2 nM).
M41864 Muscarine Muscarine ((+)-Muscarine) is a toxin that can stimulate the parasympathetic nervous system.
M41863 Milameline hydrochloride Milameline (CI 979) hydrochloride is a muscarinic receptor agonist that improves cognition.
M41862 Dipeptide diaminobutyroyl benzylamide diacetate Dipeptide diaminobutyroyl benzylamide diacetate, a Wagerlin-1-mimicking peptide, is a mAChR antagonist.




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