| Cat.No. | Name | Information |
|---|---|---|
| M2489 | Carbachol chloride | Carbachol is a cholinomimetic compound that binds and activates the acetylcholine receptor. |
| M3470 | Oxybutynin | Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties. |
| M3190 | PNU-282987 | PNU-282987 is a highly selective α7 nAChR agonist with Ki of 27 nM. |
| M52410 | SP-10 | SP-10 is a small peptide derived from S protein with an IC50 value of 1.88 nM for blocks the interaction between S protein and ACE2. |
| M49735 | hAChE-IN-6 | hAChE-IN-6 is a brain penetrant AChE inhibitor with an IC50 of 0.16 μM. |
| M49734 | AChE/GSK-3β-IN-1 | AChE/GSK-3β-IN-1 is a potent, dual AChE/GSK-3β inhibitor with IC50 values of 1.2, 149.8 and 22.4 nM for hAChE , hBChE and hGSK-3β, respectively. |
| M49732 | α7 nAchR-JAK2-STAT3 agonist 1 | α7 nAchR-JAK2-STAT3 agonist 1 is a potent α7 nAchR-JAK2-STAT3 agonist, with an IC50 value of 0.32 μM for nitric oxide (NO). |
| M49428 | α-Conotoxin AuIB TFA | α-Conotoxin AuIB TFA is a potent and selective α3β4 nicotinic acetylcholine receptor (nAChR) antagonist that blocks α3β4 nAChRs expressed in African clawed toad oocytes with an IC50 of 0.75 μM. |
| M45391 | NBI-1117570 | NBI-1117570 is an oral muscarinic M1/M4 selective dual agonist for studies related to neurological disorders. |
| M45390 | NBI-1117568 | NBI-1117568 is an oral selective muscarinic M4 receptor agonist for use in Alzheimer's disease as well as in studies related to schizophrenia. |
| M45117 | Xanomeline tartrate | Xanomeline tartrate is a potent and selective muscarinic type 1 and type 4 (M1/M4) receptor agonist that increases neuronal excitability and can be used in studies of neurological disorders such as schizophrenia. |
| M44961 | O-Desmethyl galanthamine | O-Desmethyl Galanthamine (Sanguinine) is galanthamine-type alkaloid. O-Desmethyl Galanthamine is an acetylcholinesterase (AChE) inhibitor, with an IC50 1.83 μM. |
| M44950 | N-Methylcalycinine | N-Methylcalycinine is a nature product with AChE inhibitory activity. |
| M44935 | Microgrewiapine A | Microgrewiapine A is an antagonist of nAChR. |
| M44879 | Homatropine hydrochloride | Homatropine hydrochloride is an orally active anticholinergic agent that rapidly dilates pupils and has cycloplegic effects. |
| M44877 | Homatropine | Homatropine is an orally active muscarinic acetylcholine receptor antagonist and can be used as an anticholinergic agent. |
| M44873 | Heliosupine N-oxide | Heliosupine N-oxide, Heliosupin metabolite, inhibits muscarinic acetylcholine receptor (mAChR) with the IC50 of 350 μM. Heliosupine N-oxide is a pyrrolizidine alkaloid (PA). |
| M44846 | Echimidine N-oxide | Echimidine N-oxide, a pyrrolizidine alkaloid, has acetylcholinesterase (AChE) inhibitory activity (IC50=0.347 mM). |
| M44781 | Apohyoscine | Aposcopolamine is an alkaloid that can be isolated from Datura ferox. Aposcopolamin can closely binds with ACHE, ADRA2A and CHRM2. Aposcopolamine can be used for the research of Alzheimer's disease. |
| M42669 | hBChE-IN-1 | hBChE-IN-1 and highly selective over hAChE. |
| M42668 | GSK1034702 | GSK1034702 is a M1 mAChR allosteric agonist. |
| M42667 | AChE-IN-40 | AChE-IN-40 is an AChE inhibitor (IC50: 120 nM). |
| M42666 | AChE-IN-39 | AChE-IN-39 is an AChE inhibitor (IC50: 0.058 μM). |
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