Cat.No. | Name | Information |
---|---|---|
M2489 | Carbachol chloride | Carbachol is a cholinomimetic compound that binds and activates the acetylcholine receptor. |
M3470 | Oxybutynin | Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties. |
M3190 | PNU-282987 | PNU-282987 is a highly selective α7 nAChR agonist with Ki of 27 nM. |
M52772 | αO-Conotoxin GeXIVA | αO-Conotoxin GeXIVA is a potent α9α10 nAChR antagonist with an IC50 of 12 nM against rat α9α10. |
M52771 | αA-Conotoxin OIVA | αA-Conotoxin OIVA (αA-OIVA) is a selective nAChR antagonist with an IC50 of 56 nM against mammalian fetal muscle nAChR. |
M52770 | αA-Conotoxin PIVA | αA-Conotoxin PIVA is a selective mouse musclenAChR inhibitor with IC50 for adult and fetal mouse musclenAChR sub> values are 2.3 nM and 22 nM respectively. |
M52769 | α-Conotoxin AuIA | α-Conotoxin AuIA is a potent and selective α3β4 n-nAChR inhibitor. |
M52768 | α-Conotoxin BuIA | α-Conotoxin BuIA is a paralytic peptide neurotoxin and a competitive nAChR antagonist, with IC50s of 0.258 nM (α6/α3β2), 1.54 nM (α6/α3β4), 5.72 nM (α3β2), respectively. |
M52767 | α-Conotoxin Im-I | α-Conotoxin Im-I is a selective α7/α9 nAChR antagonist, blocking α7 nicotinic receptors with the highest apparent affinity, while having an 8-fold lower affinity for homomeric α9 nicotinic receptors. |
M52766 | α-Conotoxin MrIC | α-Conotoxin MrIC is an α7nAChR biased agonist. |
M52765 | α-Conotoxin PeIA | α-Conotoxin PeIA is an analgesic α-conotoxin.α-Conotoxin PeIA inhibits the α6β4, α9α10 and α3β2 nAChR.α-Conotoxin PeIA is also a potent inhibitor of N-type calcium channel via GABAB receptor activation. |
M52764 | α-Conotoxin RgIA | α-Conotoxin RgIA (α-RgIA) is a specific α9α10 nAChR antagonist. |
M52763 | α-Conotoxin S IA | α-Conotoxin SIA is a selective nicotinic acetylcholine receptor (nAChR) antagonist with high affinity for the muscle nAChR. |
M52762 | α-Conotoxin TxID | α-Conotoxin TxID is a potent α3β4 nAChR antagonist with an IC50 value of 12.5 nM. |
M52761 | α-Conotoxin GIC | α-Conotoxin GIC is a potent and selective α3β2 nicotinic antagonist with an IC50 of 1.1 nM. |
M52760 | α-Conotoxin GID | α-Conotoxin GID is a paralytic peptide neurotoxin and a selective antagonist of nAChR, with IC50s of 5 nM (α7), 3 nM (α3β2), 150 nM (α4β2), respectively. |
M52759 | α-Conotoxin EI | α-Conotoxin EI is a selective nicotinic acetylcholine α1β1γδ receptor (nAChR) antagonist (IC50=187 nM) and an α3β4 receptor inhibitor. |
M52758 | α-Conotoxin GI | α-Conotoxin GI has high affinity for nAChR.α-Conotoxin GI is a short peptide toxin that can be isolated from the venom of Conus geographus.α-Conotoxin GI has the similar activity with neuromuscular blocking agent. |
M52757 | Azemiopsin | Azemiopsin is a potent nicotinic acetylcholine receptor (nAChR) inhibitor with IC50s of 0.18 μM and 22 μM against T. |
M52756 | Waglerin-1 | Waglerin-1, a 22-amino acid peptide, is a competitive antagonist of the muscle nicotinic receptor (nAChR). |
M52755 | ACV1 | ACV1 (Vc1.1), an α-Conotoxin, is a selective α9α10 nAChR antagonist with an IC50 of 19 nM. |
M52412 | Glycyl-L-glutamic acid | Glycyl-L-glutamic acid is a neurotrophic factor (NF) in vivo, and exerts function of maintenance of AChE content and activity. |
M52411 | Fasciculin-II | Fasciculin-II (Fas-2) is a potential inhibitor of acetylcholinesterase (AChE). |
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