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AChR/AChE Acetylcholine Receptors/Acetylcholinesterase

Cat.No.  Name Information
M2489 Carbachol chloride Carbachol is a cholinomimetic compound that binds and activates the acetylcholine receptor.
M3470 Oxybutynin Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties.
M3190 PNU-282987 PNU-282987 is a highly selective α7 nAChR agonist with Ki of 27 nM.
M5683 Glycopyrrolate Glycopyrrolate(Glycopyrronium Br) is a muscarinic competitive antagonist used as an antispasmodic.
M45390 NBI-1117568 NBI-1117568 is an oral selective muscarinic M4 receptor agonist for use in Alzheimer's disease as well as in studies related to schizophrenia.
M45117 Xanomeline tartrate Xanomeline tartrate is a potent and selective muscarinic type 1 and type 4 (M1/M4) receptor agonist that increases neuronal excitability and can be used in studies of neurological disorders such as schizophrenia.
M44961 O-Desmethyl galanthamine O-Desmethyl Galanthamine (Sanguinine) is galanthamine-type alkaloid. O-Desmethyl Galanthamine is an acetylcholinesterase (AChE) inhibitor, with an IC50 1.83 μM.
M44950 N-Methylcalycinine N-Methylcalycinine is a nature product with AChE inhibitory activity.
M44935 Microgrewiapine A Microgrewiapine A is an antagonist of nAChR.
M44879 Homatropine hydrochloride Homatropine hydrochloride is an orally active anticholinergic agent that rapidly dilates pupils and has cycloplegic effects.
M44877 Homatropine Homatropine is an orally active muscarinic acetylcholine receptor antagonist and can be used as an anticholinergic agent.
M44873 Heliosupine N-oxide Heliosupine N-oxide, Heliosupin metabolite, inhibits muscarinic acetylcholine receptor (mAChR) with the IC50 of 350 μM. Heliosupine N-oxide is a pyrrolizidine alkaloid (PA).
M44846 Echimidine N-oxide Echimidine N-oxide, a pyrrolizidine alkaloid, has acetylcholinesterase (AChE) inhibitory activity (IC50=0.347 mM).
M44781 Apohyoscine Aposcopolamine is an alkaloid that can be isolated from Datura ferox. Aposcopolamin can closely binds with ACHE, ADRA2A and CHRM2. Aposcopolamine can be used for the research of Alzheimer's disease.
M42669 hBChE-IN-1 hBChE-IN-1 and highly selective over hAChE.
M42668 GSK1034702 GSK1034702 is a M1 mAChR allosteric agonist.
M42667 AChE-IN-40 AChE-IN-40 is an AChE inhibitor (IC50: 120 nM).
M42666 AChE-IN-39 AChE-IN-39 is an AChE inhibitor (IC50: 0.058 μM).
M42665 AChE-IN-35 AChE-IN-35 is an AChE inhibitor with the IC50 of 5.88 μM.
M42664 MR2938 MR2938 is a potent AChE inhibitor, with an IC50 of 5.04 μM.
M42663 AChE-IN-30 AChE-IN-30 is an AChE inhibitor with an IC50 value of 4.4 μM.
M42662 hAChE-IN-1 hAChE-IN-1 is a potent hAChE inhibitor with an IC50 of 1.09 μM.
M42661 hAChE-IN-2 hAChE-IN-2 is a potent hAChE inhibitor, with an IC50 of 0.71 μM.
M42660 PD07 PD07 is an orally active AChE inhibitor (IC50: 0.29 μM for hAChE).




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