Cat.No. | Name | Information |
---|---|---|
M2489 | Carbachol chloride | Carbachol is a cholinomimetic compound that binds and activates the acetylcholine receptor. |
M3470 | Oxybutynin | Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties. |
M3190 | PNU-282987 | PNU-282987 is a highly selective α7 nAChR agonist with Ki of 27 nM. |
M5683 | Glycopyrrolate | Glycopyrrolate(Glycopyrronium Br) is a muscarinic competitive antagonist used as an antispasmodic. |
M45390 | NBI-1117568 | NBI-1117568 is an oral selective muscarinic M4 receptor agonist for use in Alzheimer's disease as well as in studies related to schizophrenia. |
M45117 | Xanomeline tartrate | Xanomeline tartrate is a potent and selective muscarinic type 1 and type 4 (M1/M4) receptor agonist that increases neuronal excitability and can be used in studies of neurological disorders such as schizophrenia. |
M44961 | O-Desmethyl galanthamine | O-Desmethyl Galanthamine (Sanguinine) is galanthamine-type alkaloid. O-Desmethyl Galanthamine is an acetylcholinesterase (AChE) inhibitor, with an IC50 1.83 μM. |
M44950 | N-Methylcalycinine | N-Methylcalycinine is a nature product with AChE inhibitory activity. |
M44935 | Microgrewiapine A | Microgrewiapine A is an antagonist of nAChR. |
M44879 | Homatropine hydrochloride | Homatropine hydrochloride is an orally active anticholinergic agent that rapidly dilates pupils and has cycloplegic effects. |
M44877 | Homatropine | Homatropine is an orally active muscarinic acetylcholine receptor antagonist and can be used as an anticholinergic agent. |
M44873 | Heliosupine N-oxide | Heliosupine N-oxide, Heliosupin metabolite, inhibits muscarinic acetylcholine receptor (mAChR) with the IC50 of 350 μM. Heliosupine N-oxide is a pyrrolizidine alkaloid (PA). |
M44846 | Echimidine N-oxide | Echimidine N-oxide, a pyrrolizidine alkaloid, has acetylcholinesterase (AChE) inhibitory activity (IC50=0.347 mM). |
M44781 | Apohyoscine | Aposcopolamine is an alkaloid that can be isolated from Datura ferox. Aposcopolamin can closely binds with ACHE, ADRA2A and CHRM2. Aposcopolamine can be used for the research of Alzheimer's disease. |
M42669 | hBChE-IN-1 | hBChE-IN-1 and highly selective over hAChE. |
M42668 | GSK1034702 | GSK1034702 is a M1 mAChR allosteric agonist. |
M42667 | AChE-IN-40 | AChE-IN-40 is an AChE inhibitor (IC50: 120 nM). |
M42666 | AChE-IN-39 | AChE-IN-39 is an AChE inhibitor (IC50: 0.058 μM). |
M42665 | AChE-IN-35 | AChE-IN-35 is an AChE inhibitor with the IC50 of 5.88 μM. |
M42664 | MR2938 | MR2938 is a potent AChE inhibitor, with an IC50 of 5.04 μM. |
M42663 | AChE-IN-30 | AChE-IN-30 is an AChE inhibitor with an IC50 value of 4.4 μM. |
M42662 | hAChE-IN-1 | hAChE-IN-1 is a potent hAChE inhibitor with an IC50 of 1.09 μM. |
M42661 | hAChE-IN-2 | hAChE-IN-2 is a potent hAChE inhibitor, with an IC50 of 0.71 μM. |
M42660 | PD07 | PD07 is an orally active AChE inhibitor (IC50: 0.29 μM for hAChE). |
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