About 4 results found for searched term "pan-KRAS-IN-3" (0.131 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M41934 | pan-KRAS-IN-3 | Ras |
| pan-KRAS-IN-3 is a pan-KRAS inhibitor. | ||
| M40499 | BI-2865 | Ras |
| BI-2865 is a non-covalent pan-KRAS inhibitor that binds to KRAS WT, G12C, G12D, G12V, and G13D mutants with Kd values of 6.9 nM, 4.5 nM, 32 nM, 26 nM, and 4.3 nM, respectively.It can be used in studies related to KRAS mutant tumors. | ||
| M41919 | pan-KRAS-IN-2 | Ras |
| pan-KRAS-IN-2 is a pan inhibitor of with IC50s ≤10 nM for KRAS WT and mutants (G12D, G12C, G12V, G12S, G12A, Q61H), and ＞10 μM for KRAS G13D, respectively. | ||
| M41924 | pan-KRAS-IN-4 | Ras |
| pan-KRAS-IN-4 is a potent inhibitor of KRAS with IC50s of 0.37 nM (Kras G12C), 0.19 nM (Kras G12V), respectively. | ||
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