About 4 results found for searched term "dBET1" (0.125 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M9237 | dBET1 | Epigenetic Reader Domain |
| dBET1 is a potent BRD4 protein degrader with an EC50 of 430 nM. dBET1 is a PROTAC that composes of (+)-JQ1 linked to NSC 527179 with a linker. | ||
| M9238 | dBET6 | PROTAC |
| dBET6 is a highly potent, selective and cell-permeable PROTAC connected by ligands for Cereblon and BET, with an IC50 of 14 nM, and has antitumor activity. | ||
| M10380 | dBET57 | PROTAC |
| dBET-57 | ||
| dBET57 is a novel BRD4 heterobifunctional small-molecule ligand (PROTAC) which exhibits significant and selective degradation of BRD4 BD1 but is inactive on BRD4 BD2. | ||
| M29060 | dBET23 | PROTAC |
| dBET23 is a highly effective and selective PROTAC BRD4 degrader with a DC50/5h of ~ 50 nM for BRD4BD1 protein. | ||
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